Fengxiang Wang is a Research associate at CAG, and joined us in March, 2010. She is responsible for
Managing and operating our biorepository workflow, including but not limited to: sample receiving/delivery, project management, managing orders and inventory, writing protocols, establishing sample preparation, sample quality control and training new/other lab members.
Before joining CAG, she worked as a research fellow at the AIDS Research Center at Kumamoto University, Kumamoto, Japan (2 years), CHOP (3 years), Thomas Jefferson University (5 years) pediatric practice (12 years).
She was a graduate student at AIDS Research Center, Kumamoto University, Kumamoto, Japan from April 1999 to March 2002m and a student at the Department of Pediatrics, Shanxi Medical University, P.R. of China from August 1979 to July 1984.
*(Please note that publications are updated intermittently and may not be completely up-to-date)
Identification of rare DNA sequence variants in high-risk autism families and their prevalence in a large case/control population.
Matsunami N, Hensel CH, Baird L, Stevens J, Otterud B, Leppert T, Varvil T, Hadley D, Glessner JT, Pellegrino R, Kim C, Thomas K, Wang F, Otieno FG, Ho K, Christensen GB, Li D, Prekeris R, Lambert CG, Hakonarson H, Leppert MF.
Mol Autism. 2014 Jan 27;5(1):5. doi: 10.1186/2040-2392-5-5.
Eomesodermin requires transforming growth factor-beta/activin signaling and binds Smad2 to activate mesodermal genes.
Picozzi P, Wang F, Cronk K, Ryan K.
J Biol Chem. 2009 Jan 23;284(4):2397-408. doi: 10.1074/jbc.M808704200. Epub 2008 Nov 26.
APOBEC3G upregulation by alpha interferon restricts human immunodeficiency virus type 1 infection in human peripheral plasmacytoid dendritic cells.
Wang FX, Huang J, Zhang H, Ma X, Zhang H.
J Gen Virol. 2008 Mar;89(Pt 3):722-30. doi: 10.1099/vir.0.83530-0.
Evidence that the Nijmegen breakage syndrome protein, an early sensor of double-strand DNA breaks (DSB), is involved in HIV-1 post-integration repair by recruiting the ataxia telangiectasia-mutated kinase in a process similar to, but distinct from, cellular DSB repair.
Smith JA, Wang FX, Zhang H, Wu KJ, Williams KJ, Daniel R.
Virol J. 2008 Jan 22;5:11. doi: 10.1186/1743-422X-5-11.
Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytes.
Huang J, Wang F, Argyris E, Chen K, Liang Z, Tian H, Huang W, Squires K, Verlinghieri G, Zhang H.
Nat Med. 2007 Oct;13(10):1241-7. Epub 2007 Sep 30.
The interferon-induced expression of APOBEC3G in human blood-brain barrier exerts a potent intrinsic immunity to block HIV-1 entry to central nervous system.
Argyris EG, Acheampong E, Wang F, Huang J, Chen K, Mukhtar M, Zhang H.
Virology. 2007 Oct 25;367(2):440-51. Epub 2007 Jul 12.
Alpha interferon potently enhances the anti-human immunodeficiency virus type 1 activity of APOBEC3G in resting primary CD4 T cells.
Chen K, Huang J, Zhang C, Huang S, Nunnari G, Wang FX, Tong X, Gao L, Nikisher K, Zhang H.
J Virol. 2006 Aug;80(15):7645-57.
The RNA helicase DDX1 is involved in restricted HIV-1 Rev function in human astrocytes.
Fang J, Acheampong E, Dave R, Wang F, Mukhtar M, Pomerantz RJ.
Virology. 2005 Jun 5;336(2):299-307.
IL-7 is a potent and proviral strain-specific inducer of latent HIV-1 cellular reservoirs of infected individuals on virally suppressive HAART.
Wang FX, Xu Y, Sullivan J, Souder E, Argyris EG, Acheampong EA, Fisher J, Sierra M, Thomson MM, Najera R, Frank I, Kulkosky J, Pomerantz RJ, Nunnari G.
J Clin Invest. 2005 Jan;115(1):128-37.
Peripheral blood Dendritic cells are not a major reservoir for HIV type 1 in infected individuals on virally suppressive HAART.
Otero M, Nunnari G, Leto D, Sullivan J, Wang FX, Frank I, Xu Y, Patel C, Dornadula G, Kulkosky J, Pomerantz RJ.
AIDS Res Hum Retroviruses. 2003 Dec;19(12):1097-103.
Emergence of autologous neutralization-resistant variants from preexisting human immunodeficiency virus (HIV) quasi species during virus rebound in HIV type 1-infected patients undergoing highly active antiretroviral therapy.
Wang FX, Kimura T, Nishihara K, Yoshimura K, Koito A, Matsushita S.
J Infect Dis. 2002 Mar 1;185(5):608-17. Epub 2002 Feb 14. Erratum in: J Infect Dis 2002 Jul 1;186(1):145.