The main purpose of this study is to obtain images of the brain that will help understand the effects of genes on brain development and behavior. The data will also help establish the risk of developing brain disorders in the general population.

Measures of brain structure will be provided by Magnetic Resonance Imaging (MRI). Brain activity will be measured using a technique called functional magnetic resonance imaging (fMRI). The method is accurate and non-invasive.

You/your child will complete a practice task on the computer with a trained study administrator and then escorted to the scanner. The study will be conducted at the Magnetic Resonance Imaging Facility in the Department of Radiology, University of Pennsylvania Medical Center. Although the measurement is painless, it will be somewhat noisy inside the magnet due to a hammering sound made when the magnetic field gradients are activated. Disposable earplugs will be provided to diminish the noise. While in the scanner you/your child will be presented with words, faces, or shapes and will be asked to solve problems with them.

The study will take approximately one hour to complete. At any time during or before the MRI study, and for any reason, you/your child may choose to stop the study. If you/your child withdraws from the study, participation in future studies will not be affected and compensation will be provided for time and travel in the full amount.

Before entering the scanner, you/they will be asked to fill out a scale rating how they are feeling. During this time a member of the research team will be present and will advise your child on the progress of the study.

DNA Image