CHOP Research Institute

Center for Applied Genomics

Today's Research Becomes Tomorrows Cure

The Center for Applied Genomics (CAG) was founded by Dr. Hakon Hakonarson in 2006 to study the genetic causes of childhood diseases. Since then, more than 100,000 participants and their family members have participated in our research studies, and about 10,000 CHOP patients sign up to our studies every year. If you have been asked to take part in a CAG study, you can review some common questions below, continue to our FAQs page, or This email address is being protected from spambots. You need JavaScript enabled to view it..
What is the purpose of CAG's research?
People who take part in CAG studies are joining an effort to better understand the causes of childhood disorders. By comparing children and parents who have certain medical conditions with those who don’t, we can identify genes responsible for these conditions. We use this information to work on new treatments.
Who can take part in the study?
Children who are treated at CHOP and their parents are eligible to take part. We will also approach families who attend the various specialty clinics at CHOP, and community outreach programs. Children under 18 years of age need permission from their parents to take part.
What would I need to do?
You would need to let study staff collect a teaspoon-sized blood sample from your child, typically taken at the same time as a scheduled blood test. Parents who decide to take part would need to let study staff collect a blood sample as well. Participants also need to answer a few questions and sign a written consent form giving study staff permission to access your child’s health records.
How long does the study last?
Taking part in the study requires 15 to 30 minutes.
How many people have already joined?
Over 100,000 CHOP patients and family members have participated to date.
Will I get results?
Probably not. Some CAG participants maybe asked if they would like to receive genetic test results. Even if participants do sign up to receive genetic test results, it is unlikely that results will be returned, as this type of testing is not routine.
Will I get paid?
I have questions - who do I contact?
You can check out our FAQs, or you can This email address is being protected from spambots. You need JavaScript enabled to view it..
Boy At Laptop