CHOP Research Institute

Center for Applied Genomics

Today's Research Becomes Tomorrows Cure

CAG in the Press

The Center for Applied Genomics at CHOP contributed important scientific analysis to a recent international study of the rare brain disease progressive supranuclear palsy (PSP), published on June 19 in the journal Nature Genetics.
Article by: Penn Medicine; June 19, 2011

Though autism and related disorders vary widely from person to person, certain brain changes may be at the root of the disorder
Article by: ScienceNews; May 25, 2011

A new genomics study, led by the Center for Applied Genomics at The Children's Hospital of Philadelphia, sets the stage for the first predictive diagnostic test in a serious immunodeficiency disease in children
Article by: The Children's Hospital of Philadelphia; May 11, 2011

In a novel approach that works around the gene defect in Wiskott-Aldrich syndrome, an inherited immune deficiency disorder, researchers used an alternative cell signaling pathway to significantly improve immune function in a 13-year-old boy with the disease.
Article by: Science Daily; April 14, 2011

In the decade since the Human Genome Project produced the first map of DNA sequences in the human genome, scientists throughout the world have combed through genome data to identify genes and gene variants that cause human disease. A new study suggests that researchers may need to broaden their search farther afield to pinpoint rare but powerful disease-causing mutations.
Article by: Science Centric; January 26, 2011

Our NEJM paper on genetic variations associated with risk for childhood asthma is ranked as 23andMe's number 2 genetic story of 2010.
Article by: 23andMe; January 15, 2011

A defective gene appears to contribute to most cases of childhood asthma, a finding that could lead to a better understanding of allergies, U.S. researchers reported on Wednesday.
Article by: National Post; January 1, 2011

Using a process that could help unravel the causes of a variety of complex diseases, scientists probing the genetics of height have discovered dozens more uncommon variants, adding to the nearly 200 already known.
Article by: Medpage Today; December 30, 2010

Major depression patients have a duplicated region of DNA on chromosome 5, according to a new research. The gene involved plays an important role in the development of nerve cells, adding to evidence that disruptions in neurotransmission networks form a biological basis for depression.
Article by: Scify News; December 02, 2010

Scientists at The Children's Hospital of Philadelphia have identified a number of areas along the genome that could play a role in the genetic underpinnings of eating disorders.
Article by: MSNBC; November 22, 2010