CHOP Research Institute

Center for Applied Genomics

Today's Research Becomes Tomorrows Cure

CAG in the Press

Besides adding to growing evidence that ADHD has a strong genetic underpinning, findings may help explain why those with the condition sometimes exhibit certain symptoms seen in other neurodevelopmental conditions, such as autism spectrum disorder, schizophrenia and bipolar disorder.
Article by: The Canadian Press; August 16, 2011

The Center for Applied Genomics at CHOP contributed important pediatric data to the largest-ever genetic study of multiple sclerosis (MS), published on August 11 in the journal Nature
Article by: CHOP Press; August 10, 2011

CAG scientists have contributed to the world's most detailed genetic map, culminating years of research into the DNA of African Americans and how genetic changes contribute to the risk of disease.
Article by: CHOP Press; July 23, 2011

As New Data Wave Begins, a Gene Study in One Disease Discovers Mutations in an Unrelated Disease
Article by: Chop Press; July 20, 2011

Harnessing the new generation of rapid, highly accurate gene-sequencing techniques, Gholson Lyon and colleagues have identified the disease-causing mutation in a newly characterized rare genetic disease, by analyzing DNA from just a few individuals
Article by: Genetic Engineering and Biotechnology News; June 28, 2011

To home in on the disease-causing mutation, the researchers used a new software programme, the Variant Annotation, Analysis & Search Tool (VAAST), that compared the family members' genomes with sequences from nearly 200 other people.
Article by: Nature News; June 23, 2011

The Center for Applied Genomics at CHOP contributed important scientific analysis to a recent international study of the rare brain disease progressive supranuclear palsy (PSP), published on June 19 in the journal Nature Genetics.
Article by: Penn Medicine; June 19, 2011

Though autism and related disorders vary widely from person to person, certain brain changes may be at the root of the disorder
Article by: ScienceNews; May 25, 2011

A new genomics study, led by the Center for Applied Genomics at The Children's Hospital of Philadelphia, sets the stage for the first predictive diagnostic test in a serious immunodeficiency disease in children
Article by: The Children's Hospital of Philadelphia; May 11, 2011

In a novel approach that works around the gene defect in Wiskott-Aldrich syndrome, an inherited immune deficiency disorder, researchers used an alternative cell signaling pathway to significantly improve immune function in a 13-year-old boy with the disease.
Article by: Science Daily; April 14, 2011