CHOP Research Institute

Center for Applied Genomics

Today's Research Becomes Tomorrows Cure

CAG in the Press

Scientists in Philadelphia have identified four new genes associated with the severe food allergy eosinophilic esophagitis (EoE). Because the genes appear to have roles in other allergic diseases and in inflammation, the findings may point toward potential new treatments for EoE.
Article by: Science Codex; November 21, 2014

Collaboration will bring together the premier pediatric genomics research organization, Center for Applied Genomics (CAG), with ex vivo gene therapy innovator, Medgenics.
Article by: GlobeNewswire; November 12, 2014

Scientists in Philadelphia have discovered a gene that dictates how much sleep we need, and say some of us are just programmed to need less sleep than others.
Article by: BBC; August 6, 2014

CHOP scientists have discovered a 'Thatcher gene' which allows people to survive on far less sleep than is recommended.
Article by: Daily Telegraph; August 6, 2014

Personalized medicine will be expensive in these early days of pioneering and planning. But individual genomic testing is not going to be exorbitant forever – and the ROI is gonna be big, both in patient outcomes and dollars saved."
Article by: OrthoSpine News; July 21, 2014

In the first genome-wide analysis of postsurgical pain in children, CAG researchers identified variations in genes that affect a child's need for pain-control drugs."
Article by: Medical XPress; June 30, 2014

The exact role of the Clec16a gene in encouraging susceptibility to type 1 diabetes may have been discovered recently when scientists discovered that the gene regulates the destruction of mitochondria, which are the energy factories of cells."
Article by: Medical Daily; June 21, 2014

After analyzing the DNA from thousands of patients, investigators from Children’s Hospital have uncovered several gene networks that may play important roles in autism."
Article by: GenomeWeb; June 6, 2014

By using next-generation sequencing (NGS) technologies, researchers from CHOP and BGI are one-third of the way toward their goal of sequencing 1,000 rare diseases."
Article by: CHOP Press; April 22, 2014

CAG-Penn study casts doubt on the role played by HDL ('good cholesterol' as a protective factor in heart disease."
Article by: News Medical; February 09, 2014